Biomedical Sciences Capstone
3002NSC Biomedical Sciences Capstone
Case Study Questions:
1. Look at the provided Liver panel. Using a table, evaluate how each of the metrics contributes to your understanding of Patient J’s condition. What assessment can be made from the protein? What can you include/exclude/corroborate? For each, what anatomical area of the liver is being affected?
2. As part of the liver panel, bilirubin levels are evaluated.
a) Using a simple diagram of liver system (including blood supply, liver, gut and kidney), explain the levels and type of bilirubin/urobilinogen in the Patient J’s plasma and include evidence to support these findings.
b) What clinical signs/symptoms are consistent with the BR findings?
c) What type of bilirubinemia and jaundice is Patient J experiencing?
d) If a urine sample was tested, predict the levels and forms of bilirubin/urobilinogen and causes.
3. Describe the anticipated faecal composition and cause if a stool sample was tested – colour, composition, density, aroma
4. Explain the results of the Iron Panel and which are most helpful in supporting the diagnosis?
5. Explain the results of the cardio test results in conjunction with any supporting symptoms.
6. Propose a reason for conducting a fasting blood glucose test. What does the result indicate?
7. Liver biopsy is an outdated test for diagnosis of Patient J’s primary disease state. What factors led to the doctors taking the liver biopsy? What information does the biopsy results provide?
8. What was the likely reason for his mother to donate blood?
9. Explain all Patient J’s other clinical signs and symptoms not already discussed. How does this information contribute to disease diagnosis and what is the causation of each (impotence, tanned skin, arthalgia, abdominal pain, fatigue & lethargy, spoon nails & genetic test result)?
10. Based on the results of all tests, what is the primary disease aetiology? What are the secondary disease aetiologies?